Skip to main content

Researchers Identify New Genes Linked With Schizophrenia Risk in First-of-Its-Kind Study

Researchers have made an important discovery about the causes of schizophrenia, a disease related to dementia or fragmented mentality.   Researchers have identified two genes associated with the disease as well as a third gene that carries the risk of schizophrenia and autism. Scientists involved in this research believes, this discovery can go a long way in finding a cure for these kind of diseases. Researchers at the Icahn School of Medicine found that these harmful genes are almost the same in every ethnic or racial group. The findings of this research were published in Nature Genetics . According to an estimate, about one percent of people worldwide suffering from schizophrenia. The scientists identified two risky genes, SRRM2 and AKAP11, based on a comparative analysis of gene sequencing from individuals with schizophrenia and healthy individuals. It compared a dataset of 35,828 patients with schizophrenia to 107,877 healthy or control groups and included a variety of
Post a Comment

Researchers Identify New Genes Linked With Schizophrenia Risk in First-of-Its-Kind Study

Researchers have made an important discovery about the causes of schizophrenia, a disease related to dementia or fragmented mentality.  

Researchers have identified two genes associated with the disease as well as a third gene that carries the risk of schizophrenia and autism. Scientists involved in this research believes, this discovery can go a long way in finding a cure for these kind of diseases.

Researchers at the Icahn School of Medicine found that these harmful genes are almost the same in every ethnic or racial group. The findings of this research were published in Nature Genetics. According to an estimate, about one percent of people worldwide suffering from schizophrenia.

The scientists identified two risky genes, SRRM2 and AKAP11, based on a comparative analysis of gene sequencing from individuals with schizophrenia and healthy individuals. It compared a dataset of 35,828 patients with schizophrenia to 107,877 healthy or control groups and included a variety of ethnic groups.

Recent studies have identified 8 genes as a risk factor for schizophrenia, they are mainly found in people of European white population but this study found these common genes in different ethnic groups.

According to study author Dongjing Liu, focusing on a subclass of genes, various variants were discovered that could prove helpful in better treatment of schizophrenia. Studies of people with different ancestral backgrounds have found that these deleterious rare variants of the gene lead to similar risk of schizophrenia in different groups during development.

Furthermore, it was also found that the PCLO gene, which was previously thought to cause only schizophrenia, is also responsible for autism. According to co-senior author Alexander W. Charon, associate professor at Icahn Mount Sinai, the findings also reflect changes in how brain diseases are thought of.

The gene may be clinically different in the same family. A variant of a gene can cause autism in a person while another member of the same family may have schizophrenia with the same variant. This information can provide a new way of treatment for schizophrenia and autism.

These are Key Symptoms of Schizophrenia

● Symptoms of schizophrenia usually begin to appear in adolescence or early 20s.

● Schizophrenia patient is unable to focus on anything. Not getting enough sleep causes problems in studies.

● Schizophrenia patients create an imaginary world and start making distance from the real world. Due to this, there are changes in their feelings, behavior and abilities.

● These people are not able to express their feelings properly. Get very emotional about something.

● Sometimes such things are seen or felt which are not really there.

● They are victims of delusion and many times they start believing that they have divine powers.

Recommended ⬇️

Labels:

Comments

Post a Comment

Popular posts from this blog

Eye Masks Can Really Help Improve Your Overall Quality of Sleep

Sufficient and deep sleep is essential for our health and wellness. Insufficient sleep creates many kind of physical and mental problems for our healthy life. Recently, a new research has revealed that sleeping with blindfolds increases brain function . Blindfold prevents dim lights coming from the window to falling on eyes. This does not disturb our sleep and we are able to sleep deeply. Getting enough and deep sleep at night increases our brain's ability to receive informations and communication skills. In a study published in Sleep Journal , Eye masks increases our memory and alertness. Research author Vivana Greco, from Cardiff University's School of Psychology , said the team of researchers used two types of experiments to understand how eye masks help us. The team of researchers monitored both the groups for a week. The research concluded that the cognitive level of the group using the eye mask was higher than that of the group that did not use the eye mask. T
Post a Comment
Read more

Insulin Deficiency From Insulin Gene Mutation Leads to Smaller Pancreas

A new thing has come to light about the case of insulin deficient diabetes type-1 patients. Researchers found that the pancreas of such patients is smaller than the pancreas of a healthy person.   Beta cells responsible for producing insulin make up a very small portion of the pancreas. Therefore, it was not expected to reduce the size of pancreas due to their degradation in type-1 diabetes. Researchers at Vanderbilt University Medical Center studied to a family living in Alabama and found that insulin deficiency, not autoimmune diabetes, is the primary cause of pancreatic shortening in type 1 diabetes. Four out of eight members of this family were suffering from monogenetic diabetes. It is caused by a rare mutation in the insulin gene.   This leads to insulin deficiency without autoimmunity. MRI of pancreas found that it was smaller in size and abnormal in shape in diabetic patients. This was similar to what was observed in individuals with type 1 diabetes.  The research
Post a Comment
Read more