Researchers have made an important discovery about the causes of schizophrenia, a disease related to dementia or fragmented mentality. Researchers have identified two genes associated with the disease as well as a third gene that carries the risk of schizophrenia and autism. Scientists involved in this research believes, this discovery can go a long way in finding a cure for these kind of diseases. Researchers at the Icahn School of Medicine found that these harmful genes are almost the same in every ethnic or racial group. The findings of this research were published in Nature Genetics . According to an estimate, about one percent of people worldwide suffering from schizophrenia. The scientists identified two risky genes, SRRM2 and AKAP11, based on a comparative analysis of gene sequencing from individuals with schizophrenia and healthy individuals. It compared a dataset of 35,828 patients with schizophrenia to 107,877 healthy or control groups and included a variety of
The word autophagy is derived from the Greek words 'Auto' meaning self and 'Phagy' meaning eating. Autophagy is a self-digesting mechanism responsible for removal of damaged organelles in our body . It is a normal psychological process that is responsible for the automatic digestion of cells in human body. Autophagy is the same as feeding of damaged cells. Autophagy is a lysosome dependent mechanism to remove unnecessary proteins in our body. It suggests the orderly degradation and recycling of cellular components. Autophagy maintains normal functions through protein degradation during biosynthesis, and nonfunctional long-lived proteins by lysosome. It automatically creates new cells to replace destroyed cells. This concept emerged during the 1960's , when researchers first observed that the cell could destroy its own contents to the membrane. In the 1990s , Oshinori Ohsumi used Baker's yeast to identify genes required for autophagy destructions.