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Researchers Identify New Genes Linked With Schizophrenia Risk in First-of-Its-Kind Study

Researchers have made an important discovery about the causes of schizophrenia, a disease related to dementia or fragmented mentality.   Researchers have identified two genes associated with the disease as well as a third gene that carries the risk of schizophrenia and autism. Scientists involved in this research believes, this discovery can go a long way in finding a cure for these kind of diseases. Researchers at the Icahn School of Medicine found that these harmful genes are almost the same in every ethnic or racial group. The findings of this research were published in Nature Genetics . According to an estimate, about one percent of people worldwide suffering from schizophrenia. The scientists identified two risky genes, SRRM2 and AKAP11, based on a comparative analysis of gene sequencing from individuals with schizophrenia and healthy individuals. It compared a dataset of 35,828 patients with schizophrenia to 107,877 healthy or control groups and included a variety of
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Older People Who Take Statin Drugs Have A Lower Risk of Parkinson's Disease

Consumption of any medicine indicates that a person is ill. But there are some medicines which cure the disease but its side effects cause another disease.

While there are some medicines which not only cure the disease but also prevent inevitable diseases like Parkinson.

Regarding this, an important study was conducted under the leadership of researchers from the American Academy of Neurology. This study found that elderly people who take statin drugs have a lower risk of Parkinson's disease than those who do not. The study was published in the 'Journal of Neurology'.

Parkinson's disease mainly affects the elderly. It is associated with disorders of the nervous system. Due to this, the body of the person suffering from this tremors, there is also trouble in walking, the ability of the brain to control the organs decreases.

What is a statin drug?

This medication is commonly used to lower blood cholesterol, prevent atherosclerosis (cleansing of the arteries), hardening of the arteries. It is very important to avoid these situations, as these types of conditions can eventually lead to heart attack or stroke.

Study author Shahram Ovisgharani, a scientist at Rush University Medical Center in Chicago, said that the results of our research suggest that people who use statins have a lower risk of Parkinson's disease. This is probably because these drugs may have partially protected the arteries of the brain.

He said that the results of our study are also encouraging because Parkinson's disease causes difficulty in walking in the elderly which makes them weak. Parkinson's still remains an incurable disease.

How was the study done?

About 2841 people were included in this study. The average age of these people was 76 years. At the start of the study, none of them suffered from Parkinson's. Of these, 936 people (33 percent) were taking statins. All these participants were screened for Parkinson's on an annual basis for six years, whether they developed symptoms of Parkinson's or Not.

Study Conclusion

At the end of the study, 1432 people (about 50 percent) had symptoms of Parkinson's. Whereas 418 of the 936 people who took statins (about 45 percent) developed symptoms of Parkinson's within six years. At the same time, out of 1905 people who did not take statins, symptoms of Parkinson's were seen in 1014.

The researchers found that even after including factors such as age, sex, smoking, diabetes, people taking statins had an average of 16 percent lower risk of Parkinson's.

About 80 percent of people who took statins were on moderate- or high-intensity statins. The researchers also found that those taking moderate statins had a nearly seven percent higher risk of Parkinson's than those taking high-intensity statins.

The researchers also analyzed the brains of 1,044 people who died during the study. It found that those taking statins had an average of 37 percent less atherosclerosis. Ovisghorani says, 'Although more study is needed about this, but still, based on the findings of this study, we can say that statins may be a diagnostic option for Parkinson's in the future.

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