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Researchers Identify New Genes Linked With Schizophrenia Risk in First-of-Its-Kind Study

Researchers have made an important discovery about the causes of schizophrenia, a disease related to dementia or fragmented mentality.   Researchers have identified two genes associated with the disease as well as a third gene that carries the risk of schizophrenia and autism. Scientists involved in this research believes, this discovery can go a long way in finding a cure for these kind of diseases. Researchers at the Icahn School of Medicine found that these harmful genes are almost the same in every ethnic or racial group. The findings of this research were published in Nature Genetics . According to an estimate, about one percent of people worldwide suffering from schizophrenia. The scientists identified two risky genes, SRRM2 and AKAP11, based on a comparative analysis of gene sequencing from individuals with schizophrenia and healthy individuals. It compared a dataset of 35,828 patients with schizophrenia to 107,877 healthy or control groups and included a v...
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How Does Our Brain Work? Scientists Trace The Workings of The Brain

The brain is the most important part of our body, as it guides our whole body. In other words - from here the whole body operates. Do you know how our brain works?

Recently, researchers from Technion Israel Institute of Technology have done a study, in this study it has been told that how our brain works and how it stores information.

According to researchers, there are many cells found in our brain which are called neurons. The main function of neurons is to exchange information in our body.

According to research, at the single neuron level in the brain, it has been found that computation takes place not only between neurons but also between individual neurons. This is not a simple process but a very complex process.

How was this research done?

This research not only changes our understanding about the brain but also shows how the brain works. Researchers hope to know about new things through this research.

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To uncover this mystery, technion professor Jackie Sheeler from the Ruth and Bruce Rapaport Faculty of Medicine and his team examined the brain at the single neuron level. They found that computation occurs not only in interactions between neurons, but also between each individual neuron.

Research on these cells has shown that it is not a simple but very complex calculating machine. This research was recently published in Science Magazine.

Inspection of a part of a neuron

Things are controlled by the primary motor cortex in our brain. Researchers in this field were able to determine which neuron exerts the thrust to produce motion. Professor Schiller's team was the first to examine the activity of the entire neuron as a unit, not just parts of it.

It was found that each neuron has branches known as dendrites. These are in close contact with the terminals (commonly known as axons) of other nerve cells, which allow them to interact with each other and allow communication.

A signal travels from the dendrites to the inside of the cell and is then transferred further along the axon. The number and structure of dendrites is found to vary greatly among nerve cells.

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The specific neurons that Professor Shiran's team focused on were the largest pyramidal neurons in the cortex. Neurons cells are known to move a lot. It is like a huge tree which is found in branches, sub-branches and sub-branches.

The discovery by the Technion team led to the understanding that these changes result in a weakening of the neuron's ability to calculate parallelism. It also helped to understand how neurons work and this has also given a new direction to research.

With the help of this research findings, it will help in finding better and accurate treatment of psychiatric diseases in future.

With the help of this research, Professor Schiller's team proved for the first time that neurons can be partitioned and they also show that these branches compute independently. What's more, many neurogenetic and neurodevelopmental data are likely to be associated with alterations in the ability of the neuron to process.

Information is calculated at the smallest level

The team also found in this discovery that these branches not only provide further information, but the sub-sub-branch also calculates the information it receives.

It then sends the results of the calculations to the larger sub-branch. The sub-branch then calculates the information received from all its branches and transmits it further.

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