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Researchers Identify New Genes Linked With Schizophrenia Risk in First-of-Its-Kind Study

Researchers have made an important discovery about the causes of schizophrenia, a disease related to dementia or fragmented mentality.   Researchers have identified two genes associated with the disease as well as a third gene that carries the risk of schizophrenia and autism. Scientists involved in this research believes, this discovery can go a long way in finding a cure for these kind of diseases. Researchers at the Icahn School of Medicine found that these harmful genes are almost the same in every ethnic or racial group. The findings of this research were published in Nature Genetics . According to an estimate, about one percent of people worldwide suffering from schizophrenia. The scientists identified two risky genes, SRRM2 and AKAP11, based on a comparative analysis of gene sequencing from individuals with schizophrenia and healthy individuals. It compared a dataset of 35,828 patients with schizophrenia to 107,877 healthy or control groups and included a variety of
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Lack of Sleep Not Only Increases The Mental Stress But Also Increases Fat in Our Body

Adequate sleep is essential for a healthy life. Lack of sleep can also lead to many types of physical and mental health problems. Lack of sleep also has the potential to give rise to a dreadful disease like cancer.

Recently, Mayo Clinic research has found that lack of sleep and eating disorders can lead to unhealthy fats in our body. The research was published in the Journal of the American College of Cardiology.

The study, led by Naima Kovasin, a researcher in cardiovascular medicine at the Mayo Clinic, found that lack of adequate sleep leads to an increase in total abdominal fat, or fat, by up to nine percent. In addition, it can be up to 11 percent in the intestinal part. It aggravates cardiac and metabolic diseases.

The main reason is our irregular lifestyle for this. By one estimate, about a third of adults in the US are deprived of adequate sleep because of shift work.

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Overuse of social media platforms and use of smartphones or other gadgets while sleeping are also increasing this type of problems. 

This has a major side effect - when people stay up late at night, their ability to eat increases even without physical activity.

According to the lead researcher of the study and Professor of Cardiovascular Medicine, Virend Somers, 'If a person sleeps less even in puberty, then his ability to eat will increase'. Even though his physical development is less, but the belly fat will increase significantly.

According to him, fat gets stored under our skin but due to insufficiency of sleep, it also starts accumulating dangerously in the intestines. The important thing is that after this condition, even if you try to get enough sleep, the amount of visceral fat continues to increase despite eating less and losing weight.

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Until now, visceral fat gain had not been linked to sleep insufficiency. If you do not get enough sleep even for a short period, then the fat accumulated in the intestines at that time continues to increase even after getting enough sleep. Therefore, it increases the risk of obesity in the long term. Which eventually leads to cardiovascular and metabolic diseases.

A look at the process of this study

Twelve healthy individuals were selected for the study. All were placed in an environment with admitted patients over two sessions of 21 days. In one session, some people were asked to have limited while others were asked to have normal sleep.

Three months later, the sleeping situations of the participants of both sessions were changed. During the study, participants in both groups had complete freedom to eat the food of their choice. 

The researchers also microscopically measured their calorie intake and expenditure, body composition, abdominal and visceral fat, and appetite biomarkers.

The first four days were for adaptation and during that time he was allowed nine hours of sleep. In the next week, members of the limited group were allowed to sleep for four hours, while the participants in the normal group slept for nine hours.  

After that, three days of recovery were given in which participants in both groups were asked to stay in bed for nine hours.

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